Expression of Growth Hormone Receptor 1A Messenger Ribonucleic Acid in Liver of Dairy Cows During Lactation and After Administration of Recombinant Bovine Somatotropin

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Involvement of hepatocyte nuclear factor-4 in the expression of the growth hormone receptor 1A messenger ribonucleic acid in bovine liver.

The GH receptor 1A mRNA (GHR 1A mRNA) is one of the major GHR mRNA variants that differ in the 5'-untranslated region. The GHR 1A mRNA is unique because it is exclusively expressed in liver. The objective of the present study was to understand the mechanism for the liver-specific expression of the GHR 1A mRNA in the bovine. Twenty-six kilobases of 5'-flanking region of the bovine GHR gene was c...

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ژورنال

عنوان ژورنال: Journal of Dairy Science

سال: 1999

ISSN: 0022-0302

DOI: 10.3168/jds.s0022-0302(99)75426-3